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KMID : 1161220230660100424
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Clinical and Experimental Pediatrics
2023 Volume.66 No. 10 p.424 ~ p.431
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Kidney complications associated with COVID-19 infection and vaccination in children and adolescents: a brief review
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Baek Hee-Sun
Cho Min-Hyun
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Abstract
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Coronavirus disease 2019 (COVID-19) has spread considerably across the globe, affecting numerous children and adolescents besides adults. Despite its relatively lower incidencerates in children and adolescents than in adults, some infectedchildren and adolescents exhibit a severe postinflammatoryresponse known as multisystem inflammatory syndrome inchildren, followed by acute kidney injury, a common complication. Meanwhile, few reports have been available regardingkidney complications such as idiopathic nephrotic syndromeand other glomerulopathies associated with COVID-19 infection and vaccination in children and adolescents. However,the morbidity and mortality of these complications are notexceptionally high; more importantly, causality has yet tobe clearly established. Finally, vaccine hesitancy in these agegroups should be addressed, considering the strong evidenceof COVID-19 vaccine safety and efficacy.
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KEYWORD
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COVID-19, Child, Acute kidney injury, Nephrotic syndrome, Vaccination
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